Senior Scientist, Radiochemist
Eli Lilly
- Toronto, ON
- Permanent
- Full-time
- Accelerate the development of the next-generation of radiopharmaceuticals by leading radiochemistry research and development for discovery programs.
- Produce and supply radiolabeled compounds to support the preclinical evaluation of novel radioligands.
- Support the development of cGMP radiopharmaceutical manufacturing processes to enable clinical development activities.
- Develop new radiolabeling methods and formulations for discovery and preclinical stage programs.
- Synthesize, test, and supply radiolabeled compounds for preclinical experiments
- Provide technical support for the development of cGMP radiopharmaceutical manufacturing processes.
- Prepare and deliver presentations for internal and external team meetings.
- Author development reports, manuscripts for publication in journals, and patents.
- PhD or MS degree in radiochemistry, organic chemistry, chemical engineering, or a related discipline.
- 5 to 10 years of relevant experience in radiochemistry, radiopharmaceutical manufacturing, organic chemistry, or process chemistry.
- Proven ability to work independently with strong organization and communication skills.
- Demonstrated ability to successfully prioritize projects and manage timelines in a fast-paced environment.
- Functional knowledge of GMPs and applicable FDA, EMA, Health Canada, USP, ICH and PDA guidelines.
- Experienced in radiochemistry development. Hands-on experience with imaging radioisotopes (F-18, Ga-68, Cu-64, Zr-89, In-111) and/or therapeutic radioisotopes (Lu-177, Ac-225, Tb-161, Cu-67, Pb-212) is considered an asset.
- Experienced in quality control testing of radiopharmaceuticals. Hands-on experience with radio-HPLC, radio-ITLC and GC are considered assets.
- Knowledge of environmental health and radioprotection requirements are considered assets.
- Position will require up to 10% of travel within North America. A valid passport and eligible to travel into these countries are required.
- Position requires to be onsite during the work week.
- This role works in a hospital setting and it is mandatory for all employees to complete health screens before onboarding. In the event the screen results show non-immunity, vaccines may need to be administered.