Understanding the role of RNA methylation in Sjogren disease
France
CDD
Temps-plein
Il y a 1 mois
Offer DescriptionThe Autoimmunity Research Team is seeking passionate and self-motivated post-doctoral candidates to embark on research endeavors focusing on the role of RNA methylation in mice models of Sjogren disease (SjD). The position is currently available and funded for 2 years, subject to renewal.Sjögren disease (SjD) is a prototypic systemic autoimmune disease affecting 0.1% of the population and characterized by the dysfunction of salivary and lacrimal glands, along with numerous systemic complications and an increased risk of lymphoma. For a long time orphaned by treatment, there is now a revolution under way, with several phase II and phase III trials in the field.Environment: Our team, led by Pr Xavier Mariette - within Inserm UMR 1184, CEA, Université Paris-Saclay, is dedicated to exploring the pathophysiology, epidemiology, and treatment strategies for various autoimmune conditions. Our research encompasses rheumatoid arthritis, SjD and lymphomas associated with autoimmune diseases, among other autoimmune-related disorders. We are committed to advancing our understanding of these complex diseases, investigating the underlying mechanisms driving their progression, and identifying novel therapeutic interventions. Through multidisciplinary approaches and collaborative efforts, we aim to make significant strides in improving patient outcomes and quality of life for individuals affected by autoimmune disorders. The laboratory provides state-of-the-art facilities for cellular and molecular biology, and top-level rheumatology/immunology research and an animal facility. The host lab has a particular interest in translating its basic science discoveries into translational research.Candidates: The applicants are expected to have a strong background in immunology and immunopathology (PhD), RNA biology and cellular biology as well as in mice work, including injections and organ recuperation. The ideal candidates should be highly motivated, curious, and enthusiastic to work in a highly collaborating team. Proven ability to identify research objectives and meet agreed deadlines, self-motivation, flexibility, and assistance to other ongoing research work is essential. Excellent written and communication skills in English are required. Bioinformatics and international training will constitute an advantage.Application: Candidates are invited to contact Dr. Rami Bechara ( ) for further details.Please send an application with the following:- Cover letter- Concise summary of previous research activities- Curriculum vitae including publication list and contact details for 2-3 refereesRequirementsResearch Field Biological sciences » Other Education Level PhD or equivalentSkills/QualificationsThe applicants are expected to have a strong background in immunology and immunopathology (PhD), RNA biology and cellular biology as well as in mice work, including injections and organ recuperation. The ideal candidates should be highly motivated, curious, and enthusiastic to work in a highly collaborating team. Proven ability to identify research objectives and meet agreed deadlines, self-motivation, flexibility, and assistance to other ongoing research work is essential. Excellent written and communication skills in English are required. Bioinformatics and international training will constitute an advantage.Languages ENGLISH Level ExcellentResearch Field Biological sciences » Other Years of Research Experience 1 - 4Additional InformationWork Location(s)Number of offers available 1 Company/Institute Inserm UMR 1184 Country France GeofieldWhere to apply E-mailrami.bechara@universite-paris-saclay.frContact WebsiteSTATUS: EXPIRED