Post-doctoral fellow (M/F) on smartmicroscopy for single molecules imging in depth

  • Orsay, Essonne
  • CDD
  • Temps-plein
  • Il y a 2 mois
Offer DescriptionThe Nanobio team is developing new microscopy methods to push back the limits of these observations in terms of both acquisition speed and depth of observation. This highly interdisciplinary project is aimed at candidates with different backgrounds who would like to be involved in setting up the instrument and/or analysing the data, using deep learning approaches to optimise the experimental parameters in real time. This post will involve developing a new implementation of this technique, called ModLoc for Modulated Localization, and setting up a new instrument to improve stability, resolution, acquisition speed, observation volume and analysis in real time (smart microscopy). This project will be carried out as part of the EIC Nanoscan, which includes Politechnico di Milano, CNRS, Laserlab and Abbelight, and will benefit in particular from a new generation of patented optical chip for generating structured illumination.Depending on his/her experience/training, the person will contribute to various aspects concerning the setting up of the instrument and/or the analysis of the data:
- setting up new illumination and detection methods for this new instrumental device -
- development of new real-time analysis strategies and optimisation of real-time experimental parameters
- testing and validation of the new experimental set-up - pilot/simulation programming - characterisation of various samples - writing articles - participation in conferences.This work will be carried out within ISMO (Unité Mixte CNRS / Université Paris-Saclay) as part of a European EIC Transition Nanoscan project involving 2 other laboratories, the european network Laserlab and one company (Abbelight). The laboratory has an on-site culture room and various microscopes for single molecule localization microscopy, SIM and FLIM.RequirementsResearch Field Physics Education Level PhD or equivalentLanguages FRENCH Level BasicResearch Field Physics Years of Research Experience NoneAdditional InformationEligibility criteria- optics
- microscopy
-python programming for data/imaging analysis
- knowledge of single-molecule imaging (acquisition and processing)
- knowledge of photophysics
- knowledge of cell culture
-Website for additional job detailsWork Location(s)Number of offers available 1 Company/Institute Institut des Sciences Moléculaires d'Orsay Country France City ORSAY GeofieldWhere to apply WebsiteContact CityORSAY WebsiteSTATUS: EXPIRED

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