Postdoc in Computational Biology

Syddansk Universitet

Odense, Syddanmark
Permanent
Fuldtid

23 dage siden

Job Description:The Department of Molecular Medicine is recruiting a postdoc in Computational Biology. The position is available from August 1, 2024 or as soon as possible thereafter. The position is initially for six months with the possibility of long-term extension.The Department of Molecular Medicine (IMM) aims to generate new knowledge on the function of the human body and disease mechanisms, thereby contributing to improved human health. IMM hosts an interdisciplinary group of experts in cancer biology and neurobiology and is in close proximity to the experts in genomics, proteomics and chromatin biology. Such a promising environment elicits translational collaborations with clinical practice and research toward understanding mechanisms underlying the pathophysiology of various human diseases.Applications are invited for the position of postdoc in Computational Biology in the laboratory of DNRF Chair and Novo Nordisk Faculty Professor Vijay Tiwari ( .tiwarilab.org/). Tiwari lab employ cutting-edge single-cell and spatial omics technologies with bioinformatics and machine learning to decipher principles of gene regulation. In this project, the candidate will develop new computational strategies to identify human genetic variation linked to cell fate changes in neurodevelopmental disorders and cancer. The candidate can use and combine single-cell ATAC-seq, single-cell RNA-seq, spatial gene expression, and whole-genome sequencing (with long reads) data. The candidate will get the opportunity to explore new analysis methods using deep learning. Depending on the interest, it is also possible to be involved in the wet lab, to perform single-cell sequencing and other experiments.To learn more, please refer to the selected publications from the Tiwari lab:Science Advances, 2024, in press; EMBO Mol Medicine, 2024, Apr; 16(4):823-853; Nature Communications, 2024, in press; npj Precision Oncology, 2024, Mar 12;8(1):64; Nature Cell Biology, 2022, 24, 1265-1277; Genes & Development, 2020, Sep; 34(17-18):1190-1209; Nature, 2019, Mar; 567(7746):113-117; Cell Stem Cell, 2018, Oct 4; 23(4):557; Nature Communications, 2017 Nov 15;8(1):1523; The EMBO Journal, 2016 Jan 4;35(1):24-45; J Cell Science, 2015 Dec 1;128(23):4380-94; The EMBO Journal, 2015 Aug 13;34(16):2162-81; Genome Research, 2015 Sep;25(9):1309-24; Nature Communications, 2013, Sep 27; 4:2478; Cancer Cell, 2013, 23, 768-783; PNAS, 2012 Apr 17;109(16): E934-43; Nature Genetics, 2012 Jan; 18;44(1):94-100; Nature, 2011 Dec 14;480 (7378):490-5.You will

Employ new computational strategies to identify human genetic variation linked to cell-fate changes in cancer and neurodevelopmental disorders
Analyze bulk, single-cell and multi-omics datasets
Lead projects on gene regulatory mechanisms that contribute to the development and disease
Support research and development activities within the group
Maintain accurate and detailed records of research activities
Support the group leader in everyday routines including training new group members
Support the group leader in grant applications and management
Collaborate with internal and external partners
Engage in teaching as required

Required Qualifications

PhD in Bioinformatics, Computer Science, Physics, Engineering, Bio-engineering, or equivalent
Excellent track record in Bioinformatics with at least one first-author publication, accepted or submitted
Experience with machine learning is a plus (e.g., Tensorflow/Keras/PyTorch).
Experience with software containers and/or NextFlow is a plus.
Programming experience is required (Python, R).
Strong analytical, organizational, and record-keeping skills
Interest in working in a multidisciplinary and multicultural team
Willing to collaborate with internal and external collaborators as well as support group members
Experience and interest in teaching

We offer

The possibility to engage in high-impact, multidisciplinary research
A stimulating, diverse and international research environment
An initial contract for six months, with the possibility of long-term extension
Advanced training opportunities
Highly motivated research team and international collaborations
Access to state-of-the-art equipment and facilities
A supportive scientific and social network, including mentoring and career development
A competitive salary and social benefits (e.g. health coverage, parental leave, social security etc.)
Support with practical, social, and legal aspects (e.g. housing, visa, tax etc.) through our international staff office (ISO) and the department

Further informationFurther information can be obtained by e-mail to professor Vijay Tiwari atThe application deadline is June 15, 2024, at 23.59 hrs. CEST.Conditions of employmentThe employment takes place in accordance with the agreement between the Ministry of Finance and the Central Organization of the Academics.ApplicationApplications must be submitted electronically using the link “Apply now” - see below.We strongly recommend that you read before you apply.Only applications written in English will be accepted for evaluation.The application must include (as PDF files) (please note that the application (the motivation letter) and CV must not exceed 10 MB in total):

A cover letter stating your specific interest, motivation, and qualifications for the project in question (max. two pages).
A CV
Copies of certificates/diplomas including evidence of acquisition of a PhD degree or equivalent
A complete and numbered list of publications
The 3 scientific, peer-reviewed publications that the applicant wishes to be included in the assessment of his or her scientific qualifications. (Please note that one PDF file must be attached for each publication).
A Research plan
Contact details of two referees.

Incomplete applications will not be assessed.Applications may be shortlisted.Assessment of (shortlisted) applicants will be done in accordance with the current/applicable university recruitment order. Applicants will be assessed by an expert committee, and applicant will be informed of their assessment by the university.If you experience technical problems, you must contactLiving and working in DenmarkForeign applicants will be offered as part of the employment. The (ISO) at SDU provides a variety of services for new employees, guests and people who consider applying for a job at the University of Southern Denmark.The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.

Syddansk Universitet

Ansøg nu