Associate Staff Scientist, WF Institute for Regenerative Medicine

Atrium Health Floyd

  • Winston-Salem, NC
  • Permanent
  • Full-time
  • 12 days ago
The Wake Forest Institute for Regenerative Medicine (WFIRM) is seeking post-doctoral fellows and staff scientists with demonstrated experience in bioinformatics, machine learning/artificial intelligence, tissue engineering or virology to support research into virus-host responses in three-dimensional human microphysiological models of upper airway, skin and oral mucosa. Human tissue models will be challenged with a wide range of respiratory and skin-tropic viruses, including various strains of dengue, vaccinia, mpox, influenza, parainfluenza and adenovirus. Biochemical, molecular and multiomic responses to infection will be quantified using established methods. Host responses to different viral doses will be evaluated and compared over time using traditional bioinformatic approaches. In collaboration with the Wake Forest Center for Artificial Intelligence, these data will be applied to AI/ML models to identify predictive markers of virus infection and pathogenicity.EDUCATION/EXPERIENCEDoctoral degree in computer science, mathematics, physics, or virology with two years of related research experience.ESSENTIAL FUNCTIONS * Consults with principal investigator in the planning, developing, and implementation of research projects
  • Develops experimental techniques for specimen and tissue analyses utilized in complex laboratory procedures
  • Conducts complex biological tests of viral pathogens using 2D and 3D-cell cultures, organoids, planar cellular constructs, or organ-on-a-chip platforms
  • Works with bioanalytical teams to curate data for machine learning or artificial intelligence algorithmic analyses and predictions
  • Reviews scientific journals, abstracts, and other research literature to obtain or verify additional information used in the design and development of original procedures or techniques related to the research projects
  • Prepares detailed reports on the results of experiments, discusses with principal investigator the interpretation of the results, and collaborates in the preparation of scientific manuscripts for publication
  • Supervises and coordinates the operation, training, and staffing of laboratory activities. Schedules and determines work priorities
  • Maintains facilities and equipment supplies
  • Develops and establishes laboratory work procedures, methods, and policies
  • Performs other related duties incidental to the work described herein
SKILLS/QUALIFICATIONS
  • Proficiency in English
  • Ability to listen and communicate effectively
  • For bioinformatics and ML/AI, advanced computer skills. Virology, preference for BSL3 certification
  • Ability to provide oversight and direction to laboratory personnel
  • Knowledge of medical and scientific terminology to interact with staff regarding laboratory procedures and results
  • Knowledge of scientific equipment and instruments
  • Knowledge of common safety hazards and universal precautions to establish a safe work environment

Atrium Health Floyd