Offer DescriptionHepatitis C virus (HCV) causes chronic liver disease (CHC) and hepatocellular carcinoma. HCV hijacks metabolic processes to promote viral replication, resulting in metabolic dysfunction, insulin resistance (IR), and hepatic steatosis. Furthermore, CHC is influenced by the patient's metabolic homeostasis (e.g. obesity and IR), which may worsen after HCV eradication: direct-acting antivirals (DAAs) effectively eradicate HCV but cause weight gain and worsen further metabolism/liver damage. This project will explore the molecular mechanisms underlying the interaction between CHC cofactors (HCV genotype, residual liver damage, obesity/IR, lifestyle, genetic background) and the remodeling of systemic/hepatic metabolism.RequirementsAdditional InformationEligibility criteriaEligible destination country/ies for fellows:
Italy
OTHER
Eligibility of fellows: country/ies of residence:
Italy
OTHER
Eligibility of fellows: nationality/ies:
Italy
OTHER
Website for additional job detailsWork Location(s)Number of offers available 1 Company/Institute Ministero dell'Università e della Ricerca MUR Country Italy GeofieldWhere to apply WebsiteContact CityRoma WebsiteSTATUS: EXPIRED