Senior Purification Scientist
Thermo Fisher Scientific
- Birmingham
- Permanent
- Full-time
- Assessing all technical and practical aspects of existing purification strategies and driving process improvements throughout the manufacturing teams to improve the quality and efficiency of product manufacture.
- Critically analyse production equipment and drive improvements to equipment selection and process design to maximise manufacturing performance.
- To participate in process development and transfer into manufacturing to maximise manufacturing performance.
- Lead the investigation, assessment and review of current purification manufacturing strategies.
- Lead process data collection, analysis and interpretation.
- Autonomy to Drive process improvements to yield and process performance in the current supply of intermediate protein reagents, focusing where required on alternative strategies and solutions to existing challenges
- Lead the assessment of current equipment capabilities, driving improvements in technology to align with best-in-class industry standards.
- Developing and leveraging expertise across the organization – instrumental in developing future manufacturing strategies to manufacture best in class biological reagents.
- Assessment of new product introduction to ensure best industry practice is in use.
- Assessment of non-conformance and CAPA to ensure best in class resolution of processing challenges.
- Degree in Biochemistry or equivalent scientific subject and/or higher degree in protein / immunoglobulin purification based research.
- Candidate must have significant experience in protein purification techniques, with an expectation of at least 10 years’ experience at large laboratory / pilot scale manufacturing.
- Demonstrated ability to lead Projects either through experience or recognised project management training.
- Demonstrated knowledge of modern chromatography techniques, strategies and equipment
- Demonstrated knowledge of protein biochemistry to drive process improvements.
- Thorough understanding of concentration / diafiltration techniques and equipment
- Experience of liaising with Key industry suppliers of purification technology
- Detailed understanding of purification process and equipment validation
- Project management
- The role will include a mix of office based work and some physical laboratory and pilot scale manufacturing activity