Biomarker Scientist
CK Group
- Slough, Berkshire
- Permanent
- Full-time
- Our client is recruiting for a high caliber scientist to join the team to support clinical transcriptomics as a Subject Matter Expert.
- The successful applicant will be responsible for planning and technical oversight of Biomarker Transcriptomics activities outsourced to CROs.
- Practical experience of the complete workflow for RNA sequencing experiments, from sample extraction, library preparation and quality control, sequencing runs, including troubleshooting.
- Practical experience in Molecular Biology methods, including RNA extraction from a variety of biofluids and tissue matrices, primer and probe design, quantitative PCR (real-time and/or ddPCR) and data analysis.
- Excellent organisation skills and attention to detail essential, alongside enthusiasm to strengthen existing workflows and reporting.
- Clear grasp of context of use (linking biomarker assay requirements to the usage of the data generated).
- Demonstrated ability to work flexibly in a dynamic environment to meet project needs and timelines with minimal supervision.
- Ability to work in a matrix team and communicate in a clear and timely manner with a wide range of internal and external stakeholders.
- Adaptable to changing project and organizational priorities, aligned with departmental needs.
- Experience of Protein analysis using O-LINK
- Experience working with Contract Research Organisations (CROs) to oversee method development, validation and/or sample analysis to agreed deadlines.
- Experience in tissue and biofluid collection, handling and storage in clinical settings.
- Experience of working with human tissue under the directives of the Human Tissue Act (HTA), and experience of working with samples and studies under GCP compliance.
- Practical experience in any of the following techniques would be an advantage: histology and immunohistochemistry, Immunoassay and ligand binding assays, Flow cytometry assays, LC-MS.