Biomarker Scientist

CK Group

  • Slough, Berkshire
  • Permanent
  • Full-time
  • 15 days ago
CK Group are recruiting for a Biomarker Scientist to join a global pharmaceutical company, based in Slough on a contract basis initially for 12 months.Salary:Hourly: From £20.03 PAYE or £27.27 UmbrellaBiomarker Scientist Role:
  • Our client is recruiting for a high caliber scientist to join the team to support clinical transcriptomics as a Subject Matter Expert.
  • The successful applicant will be responsible for planning and technical oversight of Biomarker Transcriptomics activities outsourced to CROs.
Your Background:Candidates should have a BSc or higher academic qualification in a biological discipline with good theoretical understanding of the principals of molecular biology and transcriptomics (in particular RNA sequencing and RT-qPCR), and the application to biomarker analysis in clinical studies.
  • Practical experience of the complete workflow for RNA sequencing experiments, from sample extraction, library preparation and quality control, sequencing runs, including troubleshooting.
  • Practical experience in Molecular Biology methods, including RNA extraction from a variety of biofluids and tissue matrices, primer and probe design, quantitative PCR (real-time and/or ddPCR) and data analysis.
  • Excellent organisation skills and attention to detail essential, alongside enthusiasm to strengthen existing workflows and reporting.
  • Clear grasp of context of use (linking biomarker assay requirements to the usage of the data generated).
  • Demonstrated ability to work flexibly in a dynamic environment to meet project needs and timelines with minimal supervision.
  • Ability to work in a matrix team and communicate in a clear and timely manner with a wide range of internal and external stakeholders.
  • Adaptable to changing project and organizational priorities, aligned with departmental needs.
Preferred * Experience of working in a pharmaceutical drug discovery and development environment.
  • Experience of Protein analysis using O-LINK
  • Experience working with Contract Research Organisations (CROs) to oversee method development, validation and/or sample analysis to agreed deadlines.
  • Experience in tissue and biofluid collection, handling and storage in clinical settings.
  • Experience of working with human tissue under the directives of the Human Tissue Act (HTA), and experience of working with samples and studies under GCP compliance.
  • Practical experience in any of the following techniques would be an advantage: histology and immunohistochemistry, Immunoassay and ligand binding assays, Flow cytometry assays, LC-MS.
Company:Our client is a is a global biopharmaceutical company focused on creating value for people living with severe diseases in immunology and neurology now and into the future.Location:This role is based at our clients site in Slough.Apply:It is essential that applicants hold entitlement to work in the UK. Please quote job reference 101277 in all correspondence.Please note:This role may be subject to a satisfactory basic Disclosure and Barring Service (DBS) check.

CK Group