About GPAS :Global Pathogen Analysis Service Ltd (GPAS Ltd) aims to revolutionise the diagnosis and treatment of infectious diseases by developing Whole Genome Sequencing-based metagenomic and individual pathogen clinical tools with the ultimate aim of developing an ‘always-on global pathogen metagenomics system with the ability to identify Pathogen X and provide early warning of disease epidemics.’Built by a long-established world-leading pathogen genomics team from the University of Oxford, supported by the cloud computing scale and security of Oracle Inc, and generously funded by Larry Ellison, GPAS is a global, turn-key solution that systematises how data from genomic sequencing is processed.GPAS Ltd is delighted to be joining the Ellison Institute of Technology, Oxford, as part of the Health and Medical Science Humane Endeavour. This partnership will ensure that we can reach our goal of developing pipelines to analyse a broader range of pathogens and deliver solutions to laboratories, hospitals, and public health organisations around the globe.The Role:Reporting to the CSO, you will have a unique and exciting opportunity to contribute to the development, evaluation, and deployment of groundbreaking bioinformatic solutions within a real-world context. We are on the lookout for exceptional talent and someone who embodies our passion, has the technical capability and sees the vast potential for global application of our products.You'll engage closely with our partners at the University of Oxford, demonstrating a mission-driven attitude and adaptability to fulfil our collective objectives. Your contributions will not only be valued but encouraged, as we seek your input on enhancing our offerings, platform, and operational practices. This role promises an opportunity to make a real difference in the world though bioinformatic and cloud-based analysis for patient, hospital and public health benefit.Primary Responsibilities:
Develop code, implement and evaluate computational/bioinformatic methods and tools to support research and development in infectious disease genomics including species prediction, AMR determination, and outbreak and relatedness information.
Creating analysis pipelines and validating various tools’ performances.
Understand various sequencing devices and data types as well have a good enough understanding of upstream laboratory processes.
Be familiar with current genomic repositories such as ENA, GenBank, GISAID etc.
Collaborate with cross-functional teams including academics, clinicians, computer scientists, biostaticians, and biologist to develop and implement data-driven strategies.
Stay abreast on the latest developments in bioinformatics and computational biology.
Be innovative and take initiate to introduce new ideas and approaches.
Manage and mentor team members, setting performance goals and providing regular feedback.
RequirementsWe are looking for someone with:
A PhD qualification in computer science, bioinformatics, computational biology, microbiology, mathematics, genetic epidemiology, genomics, machine learning or equivalent.
Strong programming skills in languages such as Bash, Python, R, Nextflow, Snakemake etc.
Experience in infectious disease genomic analysis.
Having a scientific understanding of infectious disease genomics.
3-5+ years of experience in bioinformatics and computational biology.
An established or upcoming bioinformatic publication history.
Experience with large-scale genetic data analysis using bioinformatics tools and pipelines.
Proven leadership and management skills and excellent communication skills.
Ability to work effectively in a high-growth, fast-paced, dynamic environment.
Nice to haves:
Experience using docker and working with cloud computing.
Experience with regulatory guidelines and systems e.g. FDA, CE, UKCA, EUCAST.
Familiarity with machine learning and data visualization techniques.
Experience working in a biotech or pharma industry setting.
A track record of launching an academic product in the commercial market.
BenefitsWhat we can offer:We’re a close knit, collaborative small team. We’re building a team with a people-first culture. Joining GPAS is an opportunity to help shape a cutting-edge technology with the capability to dramatically improve clinical diagnostics and treatment.· Competitive salary· 28 days holiday + 8 public bank holidays, with carry-over into the next year and additional compassionate leave· Additional employer contribution to the workplace pension scheme (5% matched)· Enhanced sick pay· Group life cover· Private Medical Insurance· Employee assistance programme· Staff training budget· Cycle to work scheme· Volunteering days· Access to Perk Box that provides special offers from a wide range of companiesGPAS Ltd is committed to promoting equal opportunities in employment, and actively encourages applications from under-represented groups in society. We are open to applications for part-time and flexible working arrangements.