Postdoctor in statistics/bioinformatics

Oslo universitetssykehus

Oslo
Midlertidlig
Fulltid

13 dager siden

About the positionThe Department of Medical Genetics at Oslo University Hospital is Norway's largest medical genetics department with over 200 employees. The department is responsible for diagnostics of rare and inherited diseases, and runs a national research infrastructure for high-throughput DNA sequencing at the Norwegian Consortium for Sequencing and Personalized Medicine ( ). The research section in the department has 7 research groups ( ) working in various fields of medical genetics, including breast cancer, the genetics of autoimmune, neurological, cardiovascular and psychiatric disorders, epigenetics causes of disease, as well as groups focusing on bioinformatics.The Department of Medical Genetics invites applications for a position as a Postdoc in the field of genetics/epigenetics, starting on 1st June 2024 or as soon as possible thereafter. The project is part of a close collaboration with the Centre for Fertility and Health (CeFH), a Centre of Excellence funded by the Norwegian Research Council, at the Norwegian institute of Public Health. The position is a fixed-term full-time position for 1 year funded by the Norwegian Cancer Society.About the research projectThe project involves the analysis of genetic, epigenetic and transcriptome data from children born by assisted reproductive technology (ART). ART use is increasing, ~10 million children have been conceived using ART, and ART procedures include in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), cryopreservation of gametes or embryos, and the use of fertility medication.
ART involves the manipulation and culturing of embryos during a period of extensive epigenetic remodeling. It is plausible that ART procedures alter the fetal epigenome, perturbing development and influencing later health.Our group, using the largest family-based EWAS study to date, recently showed that ART newborns have a global decrease in DNA methylation (Håberg, S. E. et al. Nat Commun 13, 1896). We also found 607 differentially methylated CpGs in 176 genes, including genes related to growth, neurodevelopment, and other health outcomes. The implications of these findings are unknown. The project involves futher analysing and combining the data sets (genetic, epigenetic and transcriptome) to understand the effects of ART on children and young adults.
Oslo universitetssykehus er en arbeidsplass med stort mangfold. Det mener vi er helt avgjørende for å løse de oppgavene som kreves av oss. Vi ønsker derfor at dette mangfoldet skal gjenspeiles blant søkerne til våre stillinger og oppfordrer alle til å søke uavhengig av hvem du er og hvilken bakgrunn du har.Key informationApplication deadline:19.05.2024Employer:Oslo universitetssykehus HFTown/city:OsloTitle:PostdoctorPositions:1Full-time/part-time:Full-timeEmployment type:TempPercentage of full-time:100Webcruiter ID:4805534490Start date:01.06.2024End date:31.05.2025Social sharing :Work tasksThe job involves analysis of genetic, epigenetic and transcriptome data. This is primarily a research position but also involve teaching assignments. You will contribute tothe development of the department through research of high international quality. In your daily work, you will work closely with colleagues on your project, where you willreceive supervision and guidance.Your main tasks will consist of:

Independent research of high international quality, including publications and presentations at national and international conferences.
Consideration of particular methods, theories, software etc.

Qualifications and experienceThe successful candidate must have:

PhD degree within the areas of statistics and bioinformatics.
Experience with large-scale genetic, epigenetic data and transcriptome analysis would be an advantage.
A good interpersonal skills, are inclusive and team-oriented and able to contribute to a good work environment.
A good problem-solving and analytical skills.

Personal skillsThe right candidate:

Is a highly motivated and dynamic person.
Is well organized with creative thinking.
Is inclusive and team-oriented and able to contribute to a good work environment.
Has excellent oral and written English communication skills.
Have good interpersonal and communication skills and be able to work independently as well as within a team
Enjoy working in a large and complex organisation.

We offer

A full-time position with the opportunity of an extension, depending on funding.
Salary in accordance with experience.
A workplace characterized by trust, openness and respect.
Flexible hours.
A safe workplace with good colleague support.
As a new employee in OUS, you become part of a new employee program.
Good opportunities for professional and personal development.
You become part of an important social mission.

Address: Kirkeveien 166, 0455 Oslo, NorwayContactsDr. Robert LyleEmail: robert.lyle@medisin.uio.noAbout the employerSammen med pasienten utvikler vi morgendagens behandling
Oslo universitetssykehus med våre 25 000 medarbeidere skal være en lærende og skapende organisasjon med evne til å tenke nytt. Vi skal ha en ledende rolle i utvikling av forskning og innovasjon, samt utvikling av morgendagens helsetjeneste, medisinsk behandling og presisjonsmedisin. Hos oss finner du noen av landets ledende eksperter innen sine fagfelt, og her blir du en del av Norges største helsefaglige arbeidsplass. Et inkluderende arbeidsmiljø preget av åpenhet og respekt er svært viktig for oss. Uansett hva du jobber med vil du få muligheten til å utvikle deg og benytte din kompetanse på et sted hvor det virkelig teller.

Oslo universitetssykehus

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