Research Fellow in Structural Biology of RNA Chemical Modifications

University of Birmingham

  • Birmingham
  • £34,980-44,263 per year
  • Contract
  • Full-time
  • 15 days ago
Contract Type: Fixed Term contract up to June 2027BackgroundOur international group of highly motivated and interdisciplinary structural biologists is expanding. We are looking for a Research Fellow fascinated by the structural basis of molecular functions. You will study the structure-function relationships in RNA-protein complexes involved in RNA modifications as well as the impact of chemical modifications on RNA structure. We offer unique access to first-class instrumentation for structural biology. At the national centre for biomolecular NMR spectroscopy in Birmingham (HWB-NMR), we host the best biomolecular NMR equipment available in the UK, comprising 1000, 900 and 800 MHz spectrometers equipped with cryoprobes and MAS probes for both solution- and solid-state NMR, as well as an incoming 1.2 GHz spectrometer expected in 2025. At the Midlands Regional Cryo Electron Microscope Facility in Leicester, you will have access to a 300kV Titan Krios G3 cryo-electron microscope with a direct electron-detecting camera. We have BAG access to the synchrotron at DIAMOND for small angle scattering, X-ray crystallography and many more X-ray based techniques. Fully equipped biochemistry and molecular biology laboratories, as well as extensive equipment for in cellulo work and light microscopy are available. This interdisciplinary research environment will provide you with unique development opportunities.Our globally-operating research group is embedded in a vibrant community of world-renowned scientists in the fields of genome biology, cancer research and microbiology. We believe in interdisciplinarity and we strive to integrate structural biology with functional studies in cells and whole organisms, as well as with drug design and molecular engineering.Role Summary
  • Work within specified research grants and projects and contribute to writing bids
  • Operate within area of specialism
  • Analyse and interpret research findings and results
  • Contribute to generating funding
  • Contribute to licensing or spin out deals with demonstrated commercial success (such as revenues, asset or company sales, IP generated) and/or public understanding of the discipline or similar
Person Specification
  • First degree in area of specialism and normally, a higher degree (PhD or near to completion) in Biophysics/ Biochemistry/ Chemistry/Chemical Biology/ Structural Biology or related areas or equivalent qualifications
  • Proven experience in structural biology, preferably by Nuclear Magnetic Resonance Spectroscopy, both in data acquisition and analysis
  • Track record of working successfully in a biochemical laboratory
  • High level analytical capability
  • Ability to communicate complex information clearly
  • Fluency in relevant models, techniques or methods and ability to contribute to developing new ones
  • Ability to assess resource requirements and use resources effectively
  • Understanding of and ability to contribute to broader management/administration processes
  • Contribute to the planning and organising of the research programme and/or specific research project
  • Co-ordinate own work with others to avoid conflict or duplication of effort
  • Knowledge of the protected characteristics of the Equality Act 2010, and how to actively ensure in day to day activity in own area that those with protected characteristics are treated equally and fairly
Informal enquires can be made to Teresa Carlomagno:To download the full job description and details of this position and submit an electronic application online please click on the 'Apply' button.Valuing excellence, sustaining investmentWe value diversity and inclusion at the University of Birmingham and welcome applications from all sections of the community and are open to discussions around all forms of flexible working£34,980 to £44,263 with potential progression once in post to £46,974

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