Offer DescriptionAt the Department of Chemical Engineering at Delft University of Technology we are looking for a postdoctoral researcher in synthetic organic chemistry for the development of methods for the selective functionalization of the C-terminus of peptides and proteins. The project will focus on the development of new methods as well as optimization of a recently discovered method, both with the aim of application in single molecule protein sequencing. Methods likely involve photocatalysis and click chemistry, and need to be analyzed for substrate scope and yield. The project will be carried out in a close collaboration with an industrial partner actively working in this field towards practical implementation of the related technologies. Despite having an applied focus, the project is fundamental in nature.The expected starting date is as soon as possible. The position is for 2 years.As a postdoctoral researcher you will*Carry out synthesis of reagents and testing these reagents in C-term modification of peptides*Characterize products with an array of physical chemical methods (NMR, MS, HPLC, etc)*Develop, analyze and optimize new synthetic methods*Apply methods developed on peptides to full scale proteins*Provide daily guidance to BSc and/or MSc students working with you on this project*Keep up to date with the literature related to the research project*Actively participate in the scientific discussion within the groupRequirementsSpecific RequirementsWe are looking for an ambitious candidate with a PhD in organic chemistry (or have submitted a PhD thesis prior to taking up the appointment) or relevant experience. Substantial experience in synthetic organic chemistry and affinity with biomolecular chemistry and (photo)catalysis are required.Our perfect candidate has:*A PhD in organic chemistry/ molecular catalysis / chemical biology / peptide chemistry / medicinal chemistry*Experience with synthesis and characterization of organic compounds*Experience with synthesis and characterization of peptides and other biomolecules*Experience with reaction optimization*Affinity with photocatalysis and click chemistry*Proven skills of (relatively) independent scientific writing in EnglishGood communication skills in English*Ability to collaborate and adapt to an international and multidisciplinary research team.Additional InformationBenefitsSalary and benefits are in accordance with the Collective Labour Agreement for Dutch Universities. The TU Delft offers a customisable compensation package, discounts on health insurance, and a monthly work costs contribution. Flexible work schedules can be arranged.For international applicants, TU Delft has the . This service provides information for new international employees to help you prepare the relocation and to settle in the Netherlands. The Coming to Delft Service offers a for partners and they organise events to expand your (social) network.Selection processApplications should include:(1) Curriculum Vitae (with publication list)(2) A letter of application in which you explain both your motivation and the relevance of your skills and experience for this research project.(3) Names and contact details of 2 referees.The application letter should be on topic; generic letters will cause your application to be rejected immediately. DO NOT submit general recommendation letters with your application, these will not be considered. For further information about the application procedure, please contact Ms. Veby Agus,The applications will be reviewed as soon as they are received, therefore you are invited to submit your application as soon as it is ready. We reserve the right to stop the selection procedure before the deadline once a suitable candidate has been identified.Additional commentsFor more information about this vacancy, please contact the PI, Dr. Rienk Eelkema, Department of Chemical Engineering, Website for additional job detailsWork Location(s)Number of offers available 1 Company/Institute Delft University of Technology Country Netherlands City Delft Postal Code 2628 CD Street Mekelweg 2 GeofieldWhere to apply WebsiteContact CityDelft WebsiteStreetMekelweg 2 Postal Code2628 CDSTATUS: EXPIRED